diff --git a/ext/bg/js/audio.js b/ext/bg/js/audio.js
index 9508abf0..3efcce46 100644
--- a/ext/bg/js/audio.js
+++ b/ext/bg/js/audio.js
@@ -86,6 +86,24 @@ const audioUrlBuilders = {
 
         throw new Error('Failed to find audio URL');
     },
+    'text-to-speech': async (definition, optionsContext) => {
+        const options = await apiOptionsGet(optionsContext);
+        const voiceURI = options.audio.textToSpeechVoice;
+        if (!voiceURI) {
+            throw new Error('No voice');
+        }
+
+        return `tts:?text=${encodeURIComponent(definition.expression)}&voice=${encodeURIComponent(voiceURI)}`;
+    },
+    'text-to-speech-reading': async (definition, optionsContext) => {
+        const options = await apiOptionsGet(optionsContext);
+        const voiceURI = options.audio.textToSpeechVoice;
+        if (!voiceURI) {
+            throw new Error('No voice');
+        }
+
+        return `tts:?text=${encodeURIComponent(definition.reading || definition.expression)}&voice=${encodeURIComponent(voiceURI)}`;
+    },
     'custom': async (definition, optionsContext) => {
         const options = await apiOptionsGet(optionsContext);
         const customSourceUrl = options.audio.customSourceUrl;
diff --git a/ext/bg/settings.html b/ext/bg/settings.html
index ffa5533e..15425b44 100644
--- a/ext/bg/settings.html
+++ b/ext/bg/settings.html
@@ -319,8 +319,10 @@
                         <div class="input-group-addon audio-source-prefix"></div>
                         <select class="form-control audio-source-select">
                             <option value="jpod101">JapanesePod101</option>
-                            <option value="jpod101-alternate">JapanesePod101 (alternate)</option>
+                            <option value="jpod101-alternate">JapanesePod101 (Alternate)</option>
                             <option value="jisho">Jisho.org</option>
+                            <option value="text-to-speech">Text-to-speech</option>
+                            <option value="text-to-speech-reading">Text-to-speech (Kana reading)</option>
                             <option value="custom">Custom</option>
                         </select>
                         <div class="input-group-btn"><button class="btn btn-danger audio-source-remove" title="Remove"><span class="glyphicon glyphicon-remove"></span></button></div>
diff --git a/ext/mixed/js/audio.js b/ext/mixed/js/audio.js
index 50bd321f..cf8b8d24 100644
--- a/ext/mixed/js/audio.js
+++ b/ext/mixed/js/audio.js
@@ -17,7 +17,90 @@
  */
 
 
-function audioGetFromUrl(url) {
+class TextToSpeechAudio {
+    constructor(text, voice) {
+        this.text = text;
+        this.voice = voice;
+        this._utterance = null;
+        this._volume = 1;
+    }
+
+    get currentTime() {
+        return 0;
+    }
+    set currentTime(value) {
+        // NOP
+    }
+
+    get volume() {
+        return this._volume;
+    }
+    set volume(value) {
+        this._volume = value;
+        if (this._utterance !== null) {
+            this._utterance.volume = value;
+        }
+    }
+
+    play() {
+        try {
+            if (this._utterance === null) {
+                this._utterance = new SpeechSynthesisUtterance(this.text || '');
+                this._utterance.lang = 'ja-JP';
+                this._utterance.volume = this._volume;
+                this._utterance.voice = this.voice;
+            }
+
+            speechSynthesis.cancel();
+            speechSynthesis.speak(this._utterance);
+
+        } catch (e) {
+            // NOP
+        }
+    }
+
+    pause() {
+        try {
+            speechSynthesis.cancel();
+        } catch (e) {
+            // NOP
+        }
+    }
+
+    static createFromUri(ttsUri) {
+        const m = /^tts:[^#\?]*\?([^#]*)/.exec(ttsUri);
+        if (m === null) { return null; }
+
+        const searchParameters = {};
+        for (const group of m[1].split('&')) {
+            const sep = group.indexOf('=');
+            if (sep < 0) { continue; }
+            searchParameters[decodeURIComponent(group.substr(0, sep))] = decodeURIComponent(group.substr(sep + 1));
+        }
+
+        if (!searchParameters.text) { return null; }
+
+        const voice = audioGetTextToSpeechVoice(searchParameters.voice);
+        if (voice === null) { return null; }
+
+        return new TextToSpeechAudio(searchParameters.text, voice);
+    }
+
+}
+
+function audioGetFromUrl(url, download) {
+    const tts = TextToSpeechAudio.createFromUri(url);
+    if (tts !== null) {
+        if (download) {
+            throw new Error('Download not supported for text-to-speech');
+        }
+        return Promise.resolve(tts);
+    }
+
+    if (download) {
+        return Promise.resolve(null);
+    }
+
     return new Promise((resolve, reject) => {
         const audio = new Audio(url);
         audio.addEventListener('loadeddata', () => {
@@ -46,7 +129,7 @@ async function audioGetFromSources(expression, sources, optionsContext, download
         }
 
         try {
-            const audio = download ? null : await audioGetFromUrl(url);
+            const audio = await audioGetFromUrl(url, download);
             const result = {audio, url, source};
             if (cache !== null) {
                 cache[key] = result;
@@ -56,7 +139,7 @@ async function audioGetFromSources(expression, sources, optionsContext, download
             // NOP
         }
     }
-    return {audio: null, source: null};
+    return {audio: null, url: null, source: null};
 }
 
 function audioGetTextToSpeechVoice(voiceURI) {
@@ -71,3 +154,27 @@ function audioGetTextToSpeechVoice(voiceURI) {
     }
     return null;
 }
+
+function audioPrepareTextToSpeech(options) {
+    if (
+        audioPrepareTextToSpeech.state ||
+        !options.audio.textToSpeechVoice ||
+        !(
+            options.audio.sources.includes('text-to-speech') ||
+            options.audio.sources.includes('text-to-speech-reading')
+        )
+    ) {
+        // Text-to-speech not in use.
+        return;
+    }
+
+    // Chrome needs this value called once before it will become populated.
+    // The first call will return an empty list.
+    audioPrepareTextToSpeech.state = true;
+    try {
+        speechSynthesis.getVoices();
+    } catch (e) {
+        // NOP
+    }
+}
+audioPrepareTextToSpeech.state = false;
diff --git a/ext/mixed/js/display.js b/ext/mixed/js/display.js
index cf38d09d..e0994f8a 100644
--- a/ext/mixed/js/display.js
+++ b/ext/mixed/js/display.js
@@ -197,6 +197,7 @@ class Display {
         this.options = options ? options : await apiOptionsGet(this.getOptionsContext());
         this.updateTheme(this.options.general.popupTheme);
         this.setCustomCss(this.options.general.customPopupCss);
+        audioPrepareTextToSpeech(this.options);
     }
 
     updateTheme(themeName) {