diff --git a/ext/bg/js/settings/anki.js b/ext/bg/js/settings/anki.js
index 9adb2f2a..3b0912d4 100644
--- a/ext/bg/js/settings/anki.js
+++ b/ext/bg/js/settings/anki.js
@@ -35,9 +35,15 @@ function _ankiSetError(error) {
     const node = document.querySelector('#anki-error');
     if (!node) { return; }
     if (error) {
+        const errorString = `${error}`;
         node.hidden = false;
-        node.textContent = `${error}`;
+        node.textContent = errorString;
         _ankiSetErrorData(node, error);
+
+        const node2 = document.querySelector('#anki-invalid-response-error');
+        if (node2 !== null) {
+            node2.hidden = (errorString.indexOf('Invalid response') < 0);
+        }
     } else {
         node.hidden = true;
         node.textContent = '';
diff --git a/ext/bg/settings.html b/ext/bg/settings.html
index 3e06d4b5..8c787aff 100644
--- a/ext/bg/settings.html
+++ b/ext/bg/settings.html
@@ -760,6 +760,13 @@
 
                     <div class="alert alert-danger" id="anki-error" hidden></div>
 
+                    <div class="alert alert-danger" id="anki-invalid-response-error" hidden>
+                        Attempting to connect to Anki can sometimes return an error message which includes "Invalid response",
+                        which may indicate that the value of the <strong>Interface server</strong> option is incorrect.
+                        The <strong>Show advanced options</strong> checkbox under General Options must be ticked ticked to show this option.
+                        Resetting it to the default value may fix issues that are occurring.
+                    </div>
+
                     <div class="form-group">
                         <label for="card-tags">Card tags <span class="label-light">(comma or space separated)</span></label>
                         <input type="text" id="card-tags" class="form-control">
@@ -771,7 +778,7 @@
                     </div>
 
                     <div class="form-group options-advanced">
-                        <label for="interface-server">Interface server</label>
+                        <label for="interface-server">Interface server <span class="label-light">(Default: http://127.0.0.1:8765)</span></label>
                         <input type="text" id="interface-server" class="form-control">
                     </div>