diff --git a/plugin/__init__.py b/plugin/__init__.py
index eceaa77..b947a06 100644
--- a/plugin/__init__.py
+++ b/plugin/__init__.py
@@ -20,26 +20,20 @@ import inspect
 import json
 import os
 import os.path
-import random
 import re
-import string
 import time
 import unicodedata
 
-from PyQt5 import QtCore
-from PyQt5.QtCore import QTimer
-from PyQt5.QtWidgets import QMessageBox, QCheckBox
-
 import anki
 import anki.exporting
 import anki.storage
 import aqt
 from anki.cards import Card
 from anki.consts import MODEL_CLOZE
-
 from anki.exporting import AnkiPackageExporter
 from anki.importing import AnkiPackageImporter
 from anki.notes import Note
+from aqt.qt import Qt, QTimer, QMessageBox, QCheckBox
 
 from .edit import Edit
 
@@ -391,7 +385,7 @@ class AnkiConnect:
             msg.setStandardButtons(QMessageBox.Yes|QMessageBox.No)
             msg.setDefaultButton(QMessageBox.No)
             msg.setCheckBox(QCheckBox(text='Ignore further requests from "{}"'.format(origin), parent=msg))
-            msg.setWindowFlags(QtCore.Qt.WindowStaysOnTopHint)
+            msg.setWindowFlags(Qt.WindowStaysOnTopHint)
             pressedButton = msg.exec_()
 
             if pressedButton == QMessageBox.Yes:
diff --git a/plugin/edit.py b/plugin/edit.py
index 1e063af..066df0e 100644
--- a/plugin/edit.py
+++ b/plugin/edit.py
@@ -184,7 +184,7 @@ class Edit(aqt.editcurrent.EditCurrent):
     # upon a request to open the dialog via `aqt.dialogs.open()`,
     # the manager will call either the constructor or the `reopen` method
     def __init__(self, note):
-        QDialog.__init__(self, None, Qt.Window)
+        QDialog.__init__(self, None, Qt.WindowType.Window)
         aqt.mw.garbage_collect_on_dialog_finish(self)
         self.form = aqt.forms.editcurrent.Ui_Dialog()
         self.form.setupUi(self)
diff --git a/tests/conftest.py b/tests/conftest.py
index c33f006..cb26734 100644
--- a/tests/conftest.py
+++ b/tests/conftest.py
@@ -6,7 +6,6 @@ from dataclasses import dataclass
 import aqt.operations.note
 import pytest
 import anki.collection
-from PyQt5 import QtTest
 from _pytest.monkeypatch import MonkeyPatch  # noqa
 from pytest_anki._launch import anki_running, temporary_user  # noqa
 from waitress import wasyncore
@@ -15,6 +14,11 @@ from plugin import AnkiConnect
 from plugin.edit import Edit
 from plugin.util import DEFAULT_CONFIG
 
+try:
+    from PyQt6 import QtTest
+except ImportError:
+    from PyQt5 import QtTest
+
 
 ac = AnkiConnect()
 
diff --git a/tox.ini b/tox.ini
index b615d04..c8d3a41 100644
--- a/tox.ini
+++ b/tox.ini
@@ -40,25 +40,26 @@
 #       LIBGL_ALWAYS_INDIRECT=1
 #       QTWEBENGINE_CHROMIUM_FLAGS="--disable-gpu"
 #       QT_DEBUG_PLUGINS=1
-#       ANKIDEV=true
+#       ANKIDEV=1
 
 [tox]
 minversion = 3.24
 skipsdist = true
 skip_install = true
-envlist = py38-anki{45,46,47,48,49},py39-anki50qt5
+envlist = py38-anki{45,46,47,48,49},py39-anki{50qt5,50qt6}
 
 [testenv]
 commands =
     xvfb-run python -m pytest {posargs}
 setenv =
     HOME={envdir}/home
+    anki50qt6: DISABLE_QT5_COMPAT=1
 allowlist_externals =
     xvfb-run
 deps =
     pytest==7.1.1
     pytest-forked==1.4.0
-    pytest-anki @ git+https://github.com/oakkitten/pytest-anki.git@97708344
+    pytest-anki @ git+https://github.com/oakkitten/pytest-anki.git@a0d27aa5
 
     anki45: anki==2.1.45
     anki45: aqt==2.1.45
@@ -77,3 +78,6 @@ deps =
 
     anki50qt5: anki==2.1.50
     anki50qt5: aqt[qt5]==2.1.50
+
+    anki50qt6: anki==2.1.50
+    anki50qt6: aqt[qt6]==2.1.50